XNAS · Biotechnology
Last stored close · Sep 18, 2026
Close · Sep 18, 2026
$44.44-4.94%
Model Target
available with Pro
Implied upside
vs the model target
Valuation methods
the methods behind the target
TickerWhale Score
26/100
Weak
Score components
TickerWhale View
Ionis Pharmaceuticals scores 26 out of 100 overall, which we rate weak. Valuation is its strongest area and Technical its weakest.
What helps
- Valuation
What to watch
- Technical
- Quality & growth
- Risk
Quality & growth
30%22Weak
- Revenue growth -7.4%
- EPS growth n/a
Valuation
25%62Positive
- P/E -13.0
- EV/Sales 9.5
Price history
Intraday to five-year windows are free with an account
Members switch between 1D, 1M, 6M, 1Y, 2Y and 5Y and see the live price. Signed out, this is the one-year stored series the technicals below are computed from.
Market intelligence
Peer position
#138 / 139sector rank by TickerWhale Score
TickerWhale Score 26 vs sector average 55.1 (-29.1)
Revenue growth (industry)Top 80%
Gross margin (industry)Top 13%
Return on equity (industry)Top 93%
Technical analysis
our read · what classic indicators sayTickerWhale technical read
0/100Weak vs universe
Ranks 0th of 100 covered names on our technical composite — the composite itself scores 7/100 · 25% of the TickerWhale Score
Classic chart indicators
Sell
3 buy · 5 sell · 0 neutral of 8 votes
TickerWhale rates IONS's technical setup weak — 0th percentile of the covered universe. Classic chart indicators lean sell, pointing the same way.
Moving averages
0 / 9constructive
- vs 200-day-38.4%
- vs 50-day-20.6%
Momentum
Constructive
- RSI (14)25 · buy
- Stochasticbuy
- CCIsell
- Williams %Rbuy
Trend
Weak
- ADX (14) trend strength36· trending
- MACD (12,26,9)sell(histogram -1.524)
How the classic verdict is reached
Moving averages (9) agree on sell — 0 buy vs 9 sell — and carry one vote between them.
Oscillators (7) vote individually: 3 buy · 4 sell · 0 neutral.
Result — 3 buy vs 5 sell of 8 votes = Sell. Neutral votes never decide the verdict.
Fundamentals & valuation
2026-09-18 · revised_latestValuation multiples
- P/E (TTM)-13.0 · TTM loss
- P/S (TTM)8.4
- P/B16.7
- EV/EBITDA—
- EV/Sales9.5
- PEG—
Profitability & returns
- Gross margin98.2%
- Net margin-64.7%
- ROE-121.4%
- Debt/Equity3.01
Growth
- Revenue growth (YoY)-7.4%
- EPS growth (YoY)—
Green favourable · red stretched — multiples and D/E vs industry peers, margins and growth vs absolute thresholds.
Market capitalisation — $7.4B
Fundamentals history
Reported statement totals across recent periods.
Fundamentals are stored revised/latest (ADR-009): each period reflects the most recent vendor refresh, NOT point-in-time as-reported values. Do not use this series to claim what was known on a past date.
Model Target
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Peers
| Company | Score | Pulse | P/E | P/E fwd | P/B | EV/Sales | Price | Chg | Estimate | Upside | Rev. gr. |
|---|---|---|---|---|---|---|---|---|---|---|---|
| IONSCurrentIonis Pharmaceuticals | 26 | 7 | -13.0 | — | 16.7 | 9.5 | $44.44 | -4.94% | -7.4% | ||
| EXELExelixis | 81 | 80 | 17.6 | — | 8.2 | 6.1 | $58.36 | -0.22% | +9.2% | ||
| INCYIncyte | 81 | 76 | 16.2 | — | 4.1 | 3.8 | $125.31 | -1.81% | +26.9% | ||
| ACADAcadia Pharmaceuticals | 80 | 63 | 12.4 | — | 3.6 | 3.8 | $27.29 | -0.58% | +11.8% | ||
| OSCROscar Health Inc - | 78 | 67 | 19.5 | — | 5.2 | 0.5 | $32.13 | +0.47% | +43.1% | ||
| TGTXTG Therapeutics | 77 | 73 | 20.3 | — | 14.8 | 11.5 | $56.87 | +0.71% | +76.1% |
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